New research shows that physical pressure from brain tumors or injuries triggers a "self-destruction" program in neurons, leading to irreversible brain damage.

Programmed cell death (PCD) stands at the forefront of innovation in experimental pharmacology and drug discovery, providing fundamental insights into ...

In Alzheimer's, brain cells die too soon. In cancer, dangerous cells don't die soon enough. That's because both diseases alter the way cells decide when to end their lives, a process called programmed ...

In a human body, cells are constantly making life-or-death decisions. If they make the wrong choice, the result can be cancer. It may be possible to treat diseases by influencing this behavior. In the ...

Illustration of a healthy cell (left) alongside a cell that has been affected by necrosis (right). The process of necrosis, a form of cell death, may represent one of the most promising ways to change ...

Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...

A protein involved with cell death can be manipulated to slow or reverse tumor growth, a pair of new studies in mice found. A colorized three dimensional micrographic scan of a melanoma cell. Recent ...

Scientists discovered that inhibiting the enzyme STK17B forces multiple myeloma cells into iron-driven death and makes therapies more effective. Early mouse studies show strong potential for a new ...

Immunometabolism has emerged as a central hub linking infection, inflammation, cell death, and cancer. The metabolic state of cells profoundly shapes their ...